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GPTS 2023
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Short talks
Short talks Pharmacology 3
Cardiac pharmacology and treatment
Appointment
Date:
07/03/2023
Time:
09:00
–
10:30
Location / Stream:
H1
Chair
Susanne Lutz
Göttingen / DE
Programme
09:00
–
09:15
10 Min.
5 Min.
Oral presentation
09
microRNA-21 inhibition prevents adverse cardiac remodeling and dysfunction following myocardial infarction, an effect driven by macrophages.
Ileana Duran Fernandez (Munich / DE)
Cardiac pharmacology, Immunopharmacology / inflammation / anti-infectives
09:15
–
09:30
10 Min.
5 Min.
Oral presentation
10
Characterization of molecular and ventricle-specific events in cardiac hypertrophy and subsequent failure using RNAseq and smRNA FISH in an animal model of slowly progressing disease
Liane Jurida (Gießen / DE)
Cardiac pharmacology, Disease models, drug development
09:30
–
09:45
10 Min.
5 Min.
Oral presentation
11
The Ca
2+
re-uptake inhibitor PLN
R9C
perturbs cardiac excitation/contraction coupling with implication on mitochondria and SR/ER
Theresa Brand (Würzburg / DE)
Cardiac pharmacology, Signal transduction and second messengers
09:45
–
10:00
10 Min.
5 Min.
Oral presentation
12
NO-induced cGMP generated in fibroblasts increases cardiac cAMP and phospholamban phosphorylation.
Lukas Menges (Bochum / DE)
Cardiac pharmacology, Signal transduction and second messengers
10:00
–
10:15
10 Min.
5 Min.
Oral presentation
13
Differential regulation of MMPs, apoptosis and cell proliferation by the cannabinoid receptors CB1 and CB2 in vascular smooth muscle cells and cardiac myocytes
Bettina Greiner (Berlin / DE)
Cardiac pharmacology, G-protein coupled receptors
10:15
–
10:30
10 Min.
5 Min.
Oral presentation
14
ADAM10 is upregulated in human heart failure and its pharmacological as well genetic inhibition abolishes CX3CL1-dependent leucocyte infiltration and improves survival and cardiac function after infarction
Erik Klapproth (Dresden / DE)
Cardiac pharmacology, Disease models, drug development
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