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  • Oral presentation
  • 14

ADAM10 is upregulated in human heart failure and its pharmacological as well genetic inhibition abolishes CX3CL1-dependent leucocyte infiltration and improves survival and cardiac function after infarction

Appointment

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Time:
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H1

Session

Cardiac pharmacology and treatment

Topics

  • Cardiac pharmacology
  • Disease models, drug development

Authors

Erik Klapproth (Dresden / DE), P. Klose (Dresden / DE), J. Wiedemann (Dresden / DE), A. Witt (Dresden / DE), Stephan Künzel (Dresden / DE), Stefan Weber (Dresden / DE), K. Guan (Dresden / DE), I. Kopaliani (Dresden / DE), P. Mirtschink (Dresden / DE), P. Saftig (Kiel / DE), Kristina Lorenz (Würzburg / DE; Dortmund / DE), Ali El-Armouche (Dresden / DE)

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