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Oral presentation
58

A mutation in the Btk SH2 domain, known to mediate ibrutinib resistance in chronic lymphocytic leukemia, causes a significant increase in kinase function by enhancing its binding affinity to regulatory proteins or peptides

Appointment

Date: 08/03/2023

Time: 17:54 – 18:06

Talk time: 10 Min.

Discussion time: 2 Min.

Location / Stream:

Session

Cancer pharmacology and treatment

Topics

Cancer pharmacology
Signal transduction and second messengers

Authors

Martin Wist (Ulm / DE), Sascha Endres (Ulm / DE), Peter Gierschik (Ulm / DE)