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GPTS 2023
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Martin Wist
Ulm / DE
Universitätsklinikum Ulm
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Date
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08/03/2023
17:54
–
18:06
10 Min.
2 Min.
Oral presentation
58
A mutation in the Btk SH2 domain, known to mediate ibrutinib resistance in chronic lymphocytic leukemia, causes a significant increase in kinase function by enhancing its binding affinity to regulatory proteins or peptides
Cancer pharmacology , Signal transduction and second messengers
Further involvements
08/03/2023
Poster
P190
Identification of constituents conveying signals from MYD88L265P and CXCR4 or CXCR4-WHIM mutants leading to enhanced malignancy of Waldenstrom macroglobulinemia
Immunopharmacology / inflammation / anti-infectives , Signal transduction and second messengers
08/03/2023
17:54
–
18:06
10 Min.
2 Min.
Oral presentation
58
A mutation in the Btk SH2 domain, known to mediate ibrutinib resistance in chronic lymphocytic leukemia, causes a significant increase in kinase function by enhancing its binding affinity to regulatory proteins or peptides
Cancer pharmacology , Signal transduction and second messengers
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