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Sascha Endres

Further involvements

08/03/2023
17:54 – 18:06 10 Min. 2 Min.
Oral presentation
58
A mutation in the Btk SH2 domain, known to mediate ibrutinib resistance in chronic lymphocytic leukemia, causes a significant increase in kinase function by enhancing its binding affinity to regulatory proteins or peptides
Cancer pharmacology , Signal transduction and second messengers