Das Zungenfibrom als eine seltene Form von Pharynxtumoren

Introduction: Lingual neurofibromas typically arise in patients with neurofibromatosis type 1 (NF1). Unassociated solitary forms of the benign tumor may occur sporadically in the oral cavity. A case report of a 19-year-old male with swallowing disorder for a month is presented.

Material and methods: A review of the literature in PubMed was conducted. The interviewing physician assessed the family health history. Intraoperative photos and videos documented size and location of the tumor. Histopathological features of the resected material were determined.

Results: Literature research revealed more than 10 publications in pediatric and adult patients with isolated neurofibromas/schwannomas in the oral cavity. Symptom duration varied between months to several years. In our case, the pedunculated tumor in the terminal sulcus was removed with bipolar scissors in a rigid endoscopic intervention. The solid tumor caused no relevant bleeding, and the patient was discharged from hospital after overnight stay. Histopathological examination displayed typical spindle cells beneath intact squamous mucosa with expression of S-100 protein.

Conclusion: Sporadic isolated neurofibromas of the tongue are rare but need to be evaluated in the setting of NF1-syndrome. The patient must be informed carefully and followed up in an outpatient facility to detect early recurrence.

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