Introduction: Teratoma is a rare congenital tumor that is typically benign. It primarily grows in the saccrococcygeal region. In very few cases, the tumor is located in the head or neck, and in these occasions, the tumor is extremely rarely located in the pharynx. As these are extremely rare cases no treatment guidelines exist.

Material and methods: We here present two cases of nasopharyngeal teratoma in newborn combined with a literature review.

Results: Both newborns presented with postnatal critical respiratory distress due to an almost complete nasopharyngeal obstruction, resulting in immediate intubation. During the first weeks of life, tumor extirpation was done in both cases. Follow-up visits showed no recurrence of tumor. One child underwent an adenectomy and paracentesis after developing conductive hearing loss and sleep apnea during the course of his otherwise normal development.

Conclusion/Discussion: A review of the literature on nasopharyngeal mass in newborns revealed 32 cases of nasopharyngeal teratoma in the years between 2000 and 2021. Tumors should be surgically removed as soon as possible to allow normal nasal breathing and development of the child. Follow-Up visits are crucial for detecting consequential issues.

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