Quantum-Si
There remains a need in the field of proteomics for orthogonal assays that can provide deeper visibility into parts of the proteome that are less accessible to mass spectrometry. Next-Generation Protein Sequencing™ (NGPS), developed by Quantum-Si, is poised to bridge this gap by directly interrogating protein sequence and diversity at the single-molecule level. Dr. Meredith Carpenter will provide an overview of NGPS and an update on the latest applications, including proteoform detection and protein barcoding. Dr. Neil Kelleher will then discuss his laboratory’s work on combining top-down mass spectrometry and NGPS to more comprehensively characterize the cytokine IL-6.