Clinical Proteomics I

Programm

• • Poster presentation
  • P-I-0275

  Proteomics multiplex technologies: an ideal clinical tool for biomarker discovery and precision medicine for CNS conditions

  • Houari Abdesselem (Doha / QA)

   Clinical Proteomics
• • Poster presentation
  • P-I-0276

  Investigating molecular mechanisms and novel biomarkers of postoperative recurrence in hepatocellular carcinoma: proteomic analysis of FFPE samples

  • Yuki Adachi (Tokyo / JP)

   Clinical Proteomics
• • Poster presentation
  • P-I-0277

  Identifying mass spectrometry-based biomarkers for predicting tumor recurrence in lung cancer

  • Karim Aljakouch (Heidelberg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0278

  Quantitative proteome analysis of normal and degenerated intervertebral disc tissue

  • Divya Arunachalam (Coimbatore / IN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0279

  Comprehensive proteomic and glycoproteomic profiling of Organoids derived from human hepatocellular carcinoma

  • Geul Bang (Cheongju-si / KR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0280

  Exploring the role of TMOD2 in colorectal cancer development and progression through functional proteomics

  • Rodrigo Barderas (Madrid / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0281

  High-throughput LC-MS for plasma proteomics in patients with stroke

  • Teresa Barth (Planegg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0282

  Impact of the tumor microenvironment in splenic metastasis in high-grade serous ovarian cancer revealed by quantitative proteomics

  • Nicholas Bateman (Annandale, VA / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0283

  Saliva and stool proteomic profiling revealed potential biomarkers for inflammatory bowel diseases and colorectal carcinoma

  • Ilaria Battisti (Padova / IT)

   Clinical Proteomics
• • Poster presentation
  • P-I-0284

  Phosphoproteomics and depletion studies in human serum – revealing the differences between healthy state, obesity and type 2 diabetes mellitus

  • Petra Magdolna Bertalan (Debrecen / HU)

   Clinical Proteomics
• • Poster presentation
  • P-I-0285

  Proteome signatures in urinary extracellular vesicles enable prostate cancer detection

  • Irene Bijnsdorp (Amsterdam / NL)

   Clinical Proteomics
• • Poster presentation
  • P-I-0286

  Comprehensive in vivo multiomics analysis of Alzheimer's disease pathogenesis in plasma

  • Paolo Bonini (Barcelona / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0287

  Enrichment strategies for fast and sensitive analysis of cerebrospinal fluid

  • Eva Borràs (Barcelona / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0288

  Machine learning identifies clinical sepsis phenotypes that translate to the plasma proteome level

  • Thilo Bracht (Bochum / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0289

  High sensitivity analysis of tau phospho, non-phospho, and MTBR peptides in Alzheimer's disease CSF and plasma using Orbitrap Astral

  • Gunnar Brinkmalm (Mölndal / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0290

  Targeted proteomics of synapse-associated pathological processes in neurodegenerative diseaeses

  • Ann Brinkmalm (Mölndal / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0291

  Characterizing inflammatory cytokines in plasma, tracheal aspirate, and urine samples of children hospitalized with tracheostomy-associated respiratory infections utilizing Olink technology

  • Steven Bruzek (Saint Petersburg, FL / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0292

  Plasma proteomic biomarkers of respiratory failure severity and mechanical ventilation duration among critically ill children

  • Steven Bruzek (Saint Petersburg, FL / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0293

  Development and evaluation of a novel biomarker-based risk stratification platform for obesity-related complications using targeted proteomics

  • Rachel Byrne (Dublin / IE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0294

  A carrier-based quantitative proteomics method applied to biomarker discovery in pericardial fluid

  • Amanda Jessica Campbell (Odense / DK)

   Clinical Proteomics
• • Poster presentation
  • P-I-0295

  Towards skin cohort proteomics studies: A fine-tuned MS-based workflow applied to Pachyonychia congenita

  • Sara Ceccacci (Paris / FR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0296

  Proteomic profiling uncovers key proteins in ascites extracellular vesicles from Ovarian cancer patients: insight to tumor plasticity and prognosis

  • Ting Chen (Hangzhou / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0297

  Antibodyome analysis of schizophrenia by Escherichia coli proteome microarrays

  • Chien-Sheng Chen (Tainan / TW)

   Clinical Proteomics
• • Poster presentation
  • P-I-0298

  Reducing inter-observer variability: harnessing molecular insights for clinical applications

  • Aleksandra Chojnacka (Amsterdam / NL)

   Clinical Proteomics
• • Poster presentation
  • P-I-0299

  The in vivo measure and mathematical modeling of protein turnover in multiple biological compartments and across patient cohorts

  • Jacques Colinge (Montpellier / FR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0300

  Integrating proteomics return of data into a molecular tumor board for personalized precision oncology

  • Thomas Conrads (Annandale, VA / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0301

  Molecular basis of progressive familial intrahepatic cholestasis 3. A proteomics study

  • Fernando Corrales (Madrid / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0302

  A rapid and economical workflow for protein biomarker discovery using agilent 6495D triple quadrupole LC/MS system

  • Daniel Cuthbertson (Denver, CO / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0303

  Profiling the proteome response to tamoxifen

  • Leo Dahl (Solna / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0304

  Single cell and clinical proteomics profiling in non-small cell lung cancer (NSCLC)

  • Hannah Demeke (Berlin / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0305

  Comprehensive proteomics analysis of plasma from ApoE- and LDLR- deficient mice reveals atherosclerosis biomarkers with potential application in clinic

  • Cristina Amparo Devesa Arbiol (Valencia / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0306

  Quantitative tissue analysis reveals AK2, COL1A1, & PLG protein signatures: targeted therapeutics for meningioma

  • Shamjetsabam Nandibala Devi (New Delhi / IN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0307

  Proteome changes by P2X7 receptor stimulation of microvesicles and exosomes from human glioblastoma stem cells

  • Vimal Di Virgilio (Chieti / IT)
  • Stefania Angelucci (Pescara / IT)

   Clinical Proteomics
• • Poster presentation
  • P-I-0308

  Proteomic analyses of the urothelial cancer landscape reveal highly distinct prognostic and predictive subtypes

  • Franz Dressler (Berlin / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0309

  Targeted Proteomics goes clinical as primary endpoint: a case study

  • Yvan Eb-Levadoux (Toulouse / FR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0311

  Integrating proteomics into diagnostic molecular pathology reports to support molecular tumor board decisions

  • Matthias Fahrner (Freiburg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0313

  Proteomic characterisation of clear cell renal cell carcinoma in patients with Von Hippel-Lindau Syndrome

  • Tobias Feilen (Freiburg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0314

  Impact of CFTR modulators on the blood proteome

  • Kerstin Fentker (Berlin / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0315

  The proteogenomic subgroups of relapsed Osteosarcoma

  • Joris Frenz (Heidelberg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0316

  Standardized, fully automated scalable plasma workflows enabled by the Evotip pure

  • Maurine Fucito (St. Louis, MO / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0317

  The comparison and correlation of in vitro and in vivo UPEC proteomes

  • Muhammad Naadir Ganief (Basel / CH)

   Clinical Proteomics
• • Poster presentation
  • P-I-0318

  Urine proteomic analysis of patients with schizophrenia

  • Youhe Gao (Beijing / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0319

  Urinary proteome profiling for children with autism using data-independent acquisition proteomics

  • Youhe Gao (Beijing / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0320

  Abundant serum proteins potentially discriminate normal and GDM pregnancy: from peptidome to intact proteins

  • Xi Gao (BeiJing / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0321

  DIA, DDA and PRM strategies for biomarker identification and validation in plasma cohorts of COVID-19 patients with varying severity

  • Marina Gay (Barcelona / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0322

  Multi-omics analysis of tissue and serum samples from patients suffering from Crohn's patients identifies pathological mechanisms

  • Christopher Gerner (Vienna / AT)

   Clinical Proteomics
• • Poster presentation
  • P-I-0323

  Developmental-specific proteomic vulnerabilities of Leukemia

  • Sudip Ghosh (Lund / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0324

  Proteomic signatures of Mitochondrial and immune responses as predictors of melanoma evolution

  • Jeovanis Gil Valdés (Lund / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0325

  CSF proteomic analysis across the Alzheimer's disease continuum

  • Johan Gobom (Mölndal / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0326

  Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA

  • Sandra Goetze (Zurich / CH)

   Clinical Proteomics
• • Poster presentation
  • P-I-0327

  Discovery, verification and validation of urinary protein signatures in HIV-associated nephropathy in South Africa

  • Ireshyn Govender (Pretoria / ZA)

   Clinical Proteomics
• • Poster presentation
  • P-I-0328

  Mag-Net™ Urine: Improved and complementary workflow for clinical urinary proteomics

  • Ireshyn Govender (Pretoria / ZA)

   Clinical Proteomics
• • Poster presentation
  • P-I-0329

  Quantitative SRM assay development for oral cancer prognosis in a clinical routine

  • Daniela Granato (Campinas / BR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0330

  Mass spectrometric comparison of blood matrices and sample preparation techniques. Benchmarking clinical sample SOPs and different proteolysis methods for plasma and serum by LC-MSMS in DIA mode

  • Thomas Gronauer (Munich / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0331

  In-depth analysis of the plasma proteome: Are we enriching extracellular vesicles, platelets, or soluble proteins?

  • Ida Chiara Guerrera (Paris / FR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0332

  Unraveling the molecular mechanisms of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Leveraging Proteomics and PTMs analysis for the development of precision medicine

  • Victor M. Guerrero-Sanchez (Madrid / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0333

  Proteomic Characterization of Papillary Thyroid Carcinoma with Distant Metastasis

  • Zhiqing Gui (Liaoning / CN)
  • Yaoting Sun (Hangzhou / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0334

  Sample preparation comparison for the investigation of unstable peptidomic biomarkers of hypertension in human plasma

  • Elliot John Gyedu (Leicester / GB)

   Clinical Proteomics
• • Poster presentation
  • P-I-0335

  Proteomic landscaping of high-grade serous ovarian carcinoma identifies stearoyl-CoA desaturase 5 as a potential predictive biomarker for poly(ADP-ribose) polymerase inhibitor response

  • Dohyun Han (Seoul / KR)

   Clinical Proteomics
• • Poster presentation
  • P-I-0336

  Transmembrane protein 160 (TMEM160) is involved in cell proliferation and migration in lung and cervical cancer

  • Gloria Angelina Herrera-Quiterio (Cuernavaca / MX)

   Clinical Proteomics
• • Poster presentation
  • P-I-0337

  Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory

  • M. Karoliina Hirvonen (Turku / FI)

   Clinical Proteomics
• • Poster presentation
  • P-I-0338

  A deep comparative serum proteomic analysis of Uterine Leiomyosarcoma and Uterine Leiomyoma

  • Brian Hood (Annandale, VA / US)
  • Thomas Conrads (Annandale, VA / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0339

  Uncovering H. Pylori associated and independent Gastric cancer signature by tissue phosphoproteomic analysis

  • Hsiang-En Hsu (Taipei / TW)

   Clinical Proteomics
• • Poster presentation
  • P-I-0340

  Multi-proteomics identifies knee osteoarthritis progression markers in hoffa's fat pad

  • Luojiao Huang (Maastricht / NL)

   Clinical Proteomics
• • Poster presentation
  • P-I-0341

  Effect of a western diet and age on liver proteome in male and female rats

  • Isabel Huber (Potsdam / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0342

  Proteomic strategy to mitigate off-target liabilities for targeted protein degraders

  • Martha Ingola (Wuppertal / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0343

  Integrating urine and plasma proteomics to uncover age-specific molecular signatures of pediatric diseases

  • Ericka Itang (Planegg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0344

  Novel serum biomarkers in intrahepatic cholangio-carcinoma: a pilot proteomic exploration

  • Cristina Adela Iuga (Cluj-Napoca / RO)

   Clinical Proteomics
• • Poster presentation
  • P-I-0345

  Proteomic profiling of left ventricular hypertrophy regression in severe aortic valve stenosis after valve replacement

  • Christoph F. Jacob (Goettingen / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0346

  Acrivon Predictive Precision Proteomics (AP3)-guided development and prospective clinical Phase 2 validation of the response-predictive OncoSignature test for the CHK1/2 inhibitor, ACR-368

  • Magnus E. Jakobsson (Lund / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0347

  Advancing clinical diagnostics and prognostics through proteomics: insights from core facility perspective

  • Mohamed Ali Jarboui (Tuebingen / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0348

  Proteomic and proteogenomic characterization of triple negative breast cancer

  • Henrik Johansson (Solna / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0349

  Optimization of SAX-Based enrichment of plasma extracellular vesicles for high-throughput deep phenotyping of the heart failure syndrome

  • Anna Maria Jozefowicz (Mainz / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0350

  Urinary proteomic analysis reveals new molecular subtypes of lupus nephritis

  • Qin Jun (Beijing / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0351

  Proteomes, including (auto)antibody repertoires, correlate remarkably well in paired plasma and synovial fluids from rheumatoid arthritis patients

  • Sofia Kalaidopoulou Nteak (Utrecht / NL)

   Clinical Proteomics
• • Poster presentation
  • P-I-0352

  The tape-stripping procedure for the identification of protein N-termini within skin specimens

  • Patrick Kaleja (Kiel / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0353

  Salivary chemical barrier proteins in oral squamous cell carcinoma – alterations in the defense mechanism of the oral cavity

  • Gergő Kalló (Debrecen / HU)

   Clinical Proteomics
• • Poster presentation
  • P-I-0354

  Exosomal protein biomarkers for early prediction for dengue severity in pediatric population using quantitative proteomics approach

  • Anushka Singh (New Delhi / IN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0355

  Benchmarking sample preparation and data analysis for clinical proteomics of human biofluids

  • Giada Marino (Neuried / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0356

  Providing an analytical platform for state-of-the-art absolute apolipoprotein quantification in human blood plasma using prm-PASEF

  • Stephanie Kaspar-Schoenefeld (Bremen / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0357

  Streamlined extraction of proteins from clinical Trizol samples via aggregate capture on magnetic beads

  • Aigerim Kassym (Jena / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0358

  Identification of novel prognostic protein biomarkers from maternal serum of women with recurrent pregnancy loss

  • Drosos Katsavelis (Groningen / NL)

   Clinical Proteomics
• • Poster presentation
  • P-I-0359

  Profiling the blood proteome in autoimmune disease using proximity extension assay

  • Josefin Kenrick (Solna / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0360

  Impact of non-aqueous fluid flow on protein profile in glaucoma drainage device implants

  • Alka Khera (Chandigarh / IN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0361

  Proteomic strategies uncover novel aging and age-related disease signatures in the human post-menopausal ovary

  • Christina King (Novato, CA / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0362

  Proteomic profiling of circulating tumor cells for precision oncology

  • Melissa Klingeberg (Berlin / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0363

  Nanoparticle-based proteomics analysis of human biofluid samples from different patient cohorts

  • Giada Marino (Neuried / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0364

  Proteomic alterations in early-stage breast cancer: insights from tumor-adjacent normal tissues analysis

  • Po-Hsin Kong (Taipei / TW)

   Clinical Proteomics
• • Poster presentation
  • P-I-0365

  Ubiquitin: characterization of a host cell protein covalently attached to a monoclonal antibody product by LC-MS/MS

  • Regina Kufer (Penzberg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0366

  Targeted proteomic analysis for monitoring of multiple myeloma progression

  • Rudolf Kupcik (Hradec Kralove / CZ)

   Clinical Proteomics
• • Poster presentation
  • P-I-0367

  Proteomic profiling of preeclampsia

  • Magdalena Kuras (Lund / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0368

  Quantitative assessment of multiple pathogen exposure, autoimmunity and immune dynamics at scale

  • Joshua LaBaer (Tempe, AZ / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0369

  Predictive biomarker discovery for immune checkpoint inhibitor in metastatic MMRd endometrial cancer through deep proteomic profiling of FFPE tissue samples

  • Despina Stefanoska (Schlieren / CH)

   Clinical Proteomics
• • Poster presentation
  • P-I-0370

  Plasma protein biomarker discovery for ovarian cancer

  • Ryan Lamers (Waltham, MA / US)

   Clinical Proteomics
• • Poster presentation
  • P-I-0371

  Personalized tissue and liquid biopsy proteomics identify treatment targets and inform patient care

  • Philipp Lange (Vancouver / CA)

   Clinical Proteomics
• • Poster presentation
  • P-I-0372

  Exploring proteomic signatures of high-grade serous carcinoma of the ovary

  • Roberto Leguizamon (Freiburg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0373

  Decoding CRC progression: impact of patient individuality on the proteomic phenotype

  • Agnes Lengenfeld (Luebeck / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0374

  Proteomics uncovers the underlying mechanism of distant metastasis in follicular thyroid carcinoma

  • Yaoting Sun (Hangzhou / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0375

  Mitochondrial Proteomic Characterization of Thyroid Oncocytic Tumors: Diagnostic Potential of IDH2 as a Biomarker

  • Yaoting Sun (Hangzhou / CN)

   Clinical Proteomics
• • Poster presentation
  • P-I-0376

  Serum proteomic analysis reveals molecular features for stratification of chronic obstructive pulmonary disease

  • Wen-Yi Liu (Taipei / TW)

   Clinical Proteomics
• • Poster presentation
  • P-I-0377

  Revolutionizing Proteomics: Advanced nanoESI Ion Source with NanoElectrospray Emitters for Unmatched Sensitivity and Robustness

  • Daniel Lopez Ferrer (Las Matas / ES)

   Clinical Proteomics
• • Poster presentation
  • P-I-0378

  Revealing protein profiles in Parkinson's disease by mass spectrometric analysis of living brain tissue during deep brain stimulation

  • Saskia Leonie Ludwig (Cologne / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0379

  Single-shot mass spectrometry-based phosphoproteomic analysis of patient-derived formalin-fixed, parrafin-embedded samples reveal tissue specific fingerprints

  • Maximilian Maldacker (Freiburg / DE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0380

  Pathophysiological subtypes of mild cognitive impairment due to Alzheimer"s disease identified by CSF proteomics

  • Bruno Manadas (Cantanhede / PT)

   Clinical Proteomics
• • Poster presentation
  • P-I-0381

  Addressing inter-individual variability in CSF levels of brain-derived proteins across neurodegenerative diseases

  • Anna Månberg (Solna / SE)

   Clinical Proteomics
• • Poster presentation
  • P-I-0382

  Mining proteomic signature of soft tissue sarcoma by mass-spectrometry to find new candidate drug targets

  • Veronica De Giorgis (Novara / IT)

   Clinical Proteomics
• • Poster presentation
  • P-I-0383

  Investigation of inter- and intra-day variability of tear fluid in terms of flow rate, protein concentration and protein composition

  • Caroline May (Bochum / DE)

   Clinical Proteomics