23rd Human Proteome Organization World Congress

Cell lines recapitulate the kinase activity profiles of colorectal tumor tissue and predict drug response

Clinical Proteomics

Clinical Proteomics II

Poster presentation

Proteogenomic analysis revealed prognosis biomarker and therapeutic targets in sarcomas

Proteomics in oncology

Oral presentation

Kinome-profiling using patient-derived cell lines to discover novel therapeutic targets for treating dermatofibrosarcoma protuberans with resistance to imatinib

Cell Biology Insights

Integrative study of patient-derived in-vitro model toward pharmaco-proteogenomics

Pharmaco-proteogenomics for synovial sarcoma towards novel therapy

Investigating molecular mechanisms and novel biomarkers of postoperative recurrence in hepatocellular carcinoma: proteomic analysis of FFPE samples

Clinical Proteomics I

<p>The world of proteomics presents a unique set of challenges to analytical laboratories, whether they are working in untargeted global proteomics or targeted peptide profiling and quantitation. Despite developments in LC-MS technology, the inherent complexities of proteins, along with the need to increase protein coverage and peptide sequencing depth across all biological matrices, remain significant hurdles. Optimal, robust, and reproducible sample preparation workflows not only enable better quality results, but also ensure other critical requirements, such as scalability and throughput.</p><p>Covaris’ breakfast workshop at the World HUPO 2024 in Dresden, Germany, will highlight its Adaptive Focused Acoustics® (AFA®) Technology-enabled comprehensive sample preparation workflows and kits that ensure reliable, reproducible extraction, purification, and digestion of proteins from a host of complex biological matrices – ranging from cells to formalin fixed, paraffin embedded (FFPE) samples.</p>

Tadashi Kondo

Vorsitz

Vortrag

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