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GfV 2023
Programm
Poster
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Poster Session
Poster exhibition
Antiviral therapy and resistance
Termin
Datum:
28.03.2023
Zeit:
13:00
–
21:00
Ort / Stream:
Antiviral therapy and resistance
Programm
Poster
P 019
Cyclosporin A inhibits VSV infection by RIG-I mediated induction of CMPK2
Lars Meier (Marburg / DE)
Antiviral therapy and resistance, Innate immunity
Poster
P 020
Novel antivirals targeting the human cytomegalovirus alkaline nuclease UL98
Tianyu Zhang (Hamburg / DE)
Antiviral therapy and resistance
Poster
P 021
IFNα subtype-specific susceptibility of HBV in the course of chronic infection
PD Dr. Kathrin Sutter (Essen / DE)
Antiviral therapy and resistance, Host cell factors and modulation
Poster
P 022
Preclinical development of optimized DHODH inhibitors as broad-spectrum antivirals for the treatment of respiratory virus infections
Dr. Alexandra Herrmann (Gräfelfing / DE)
Antiviral therapy and resistance, Host cell factors and modulation
Poster
P 024
Validation of the cytomegalovirus nuclear egress complex as an antiviral target – assessment of covalently binding warhead compounds
Julia Tillmanns (Erlangen / DE)
Prof. Dr. Manfred Marschall (Erlangen / DE)
Antiviral therapy and resistance, Structure, assembly, egress
Poster
P 025
Automated high-throughput image-based screen discovers members of the Akt serine/threonine kinase family as potential targets for treatment of HEV virus infection
Mara Klöhn (Bochum / DE)
Antiviral therapy and resistance, Host cell factors and modulation
Poster
P 026
Identification of a selective glucocorticoid receptor modulator as HIV-1 latency-reversing agent
Dr. Sharmeen Fayyaz (Tuebingen / DE)
Antiviral therapy and resistance, Viral pathogenesis and persistence
Poster
P 027
Development of a liposomal formulation pipeline for inhalation application against SARS-CoV-2
Philipp Reus (Frankfurt / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 029
Broad-spectrum antiviral diazadispiroalkane core molecules block attachment and cell-to-cell spread of Herpesviruses
Marie Knoblauch (Berlin / DE)
Prof. Dr. Elke Bogner (Berlin / DE)
Antiviral therapy and resistance, Virus receptors and entry
Poster
P 030
Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs
Dr. Raphael Jami (Tuebingen / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 031
Regulation of SAMHD1 upon HCMV infection and potential of CDK4/6 inhibitors to suppress HCMV replication in macrophages
Georgios Vavouras Syrigos (Tuebingen / DE)
Antiviral therapy and resistance, Host cell factors and modulation
Poster
P 032
Resistance barrier, biological stability and binding properties of platelet-derived-growth-factor receptor alpha derivatives developed for inhibition of human cytomegalovirus
Prof. Dr. Christian Sinzger (Ulm / DE)
Antiviral therapy and resistance, Virus receptors and entry
Poster
P 033
A novel approach to bridge the gap from virology research to new antivirals
Dr. Andreas Kühbacher (Wuppertal / DE)
Antiviral therapy and resistance
Poster
P 034
Analysis of mutational history of multidrug-resistant genotypes with a mutagenetic tree model
Martin Pirkl (Cologne / DE)
Antiviral therapy and resistance
Poster
P 035
Effects of SARS-CoV-2 infection on GSK3 phosphorylation and the use of specific GSK3 inhibitors as antivirals
Dr. Natalia Ruetalo Buschinger (Tuebingen / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 036
Insights into the antiviral activity of
Hypericum perforatum
extract and its ingredient hypericin
Fakry F. Mohamed (Muenster / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 037
Human endogenous peptides derived from hemoglobin alpha reduce pro-viral autophagy
Dennis Freisem (Ulm / DE)
Antiviral therapy and resistance, Innate immunity
Poster
P 038
ATO (
Arsenic Trioxide
) impedes efficient HBV infection by interferance with PML-NBs
Dr. Samuel Hofmann (Hannover / DE)
Antiviral therapy and resistance, Host cell factors and modulation
Poster
P 039
Trans-delivery of defective interfering RNAs hampers replication of morbilliviruses
Oliver Siering (Langen / DE)
Antiviral therapy and resistance, Innate immunity
Poster
P 040
Combining latency-reversing agents with type I IFNs accumulates HIV-1 Env on the cell surface and sensitizes for the elimination of HIV-reactivating cells through antibody-dependent cellular cytotoxicity
Julia Kazmierski (Berlin / DE)
Antiviral therapy and resistance, Viral pathogenesis and persistence
Poster
P 041
Pyrosequencing analysis for molecular resistance marker PA-I38X of influenza A viruses to baloxavir marboxil
Dr. Susanne Duwe (Berlin / DE)
Antiviral therapy and resistance
Poster
P 042
Antiviral activity of small molecules targeting the nsp10/nsp14 complex of coronaviruses
Natalie M. Köhler (Hannover / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 043
Druggability assessment of the bunyaviral cap-binding domain
Janna Scherf (Hamburg / DE)
Antiviral therapy and resistance, Viral replication strategies 1 (RNA viruses)
Poster
P 044
Systematic comparison of latency reversing agents on transcription of human T-cell leukemia virus type 1
Louisa Rasp (Erlangen / DE)
Antiviral therapy and resistance, Viral pathogenesis and persistence
Poster
P 045
Chimeric antigen receptors as a novel treatment option for cytomegalovirus infections
Christopher Bednar (Erlangen / DE)
Antiviral therapy and resistance
Poster
P 046
In vitro
screening of a compound library targeting the sphingolipid metabolism reveals potential inhibitors of coronaviral replication
Florian Salisch (Giessen / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 047
HIV-1 N VPR mediates resistance to integrase inhibitors
Shenglin Zhu (Duesseldorf / DE)
Antiviral therapy and resistance
Poster
P 048
In vitro efficacy testing of broad-spectrum antivirals Remdesivir, Molnupiravir and Favipiravir in combination with p38 MAPK inhibition against the human pathogenic
Puumala orthohantavirus
Dr. Daniel Bourquain (Berlin / DE)
Antiviral therapy and resistance, Emerging viruses and zoonosis
Poster
P 049
A comprehensive study of wt and Omicron M
pro
mutations
Francesco Costacurta (Innsbruck / AT)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 050
Advanced molecular tweezers with lipid anchors against SARS‑CoV-2 and other respiratory pathogen
Tatjana Weil (Ulm / DE)
Antiviral therapy and resistance, Emerging viruses and zoonosis
Poster
P 051
Morus alba root bark extracts – multipotent herbal anti-infectives?
Prof. Dr. Michaela Schmidtke (Jena / DE)
Antiviral therapy and resistance
Poster
P 052
Identification and evaluation of a novel tribenzamide derivative as an inhibitor targeting the entry of the respiratory syncytial virus
PD Dr. Thomas Grunwald (Leipzig / DE)
Antiviral therapy and resistance
Poster
P 053
Replication of primary HIV-1 strains in macrophages and virus transmission to T cells
Sabina Victoria Montero (Tuebingen / DE)
Antiviral therapy and resistance, Viral pathogenesis and persistence
Poster
P 054
Identification of small molecule inhibitors against adenoviral infection
Dr. Wing Hang Ip (Hamburg / DE)
Antiviral therapy and resistance, Viral pathogenesis and persistence
Poster
P 055
Identifying novel antivirals and their targets in coronavirus-infected cells
Talia Schneider (Hannover / DE)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 056
Drug resistance associated mutations in splicing regulatory elements affecting HIV-1 gene expression and replication capacity
Lisa Müller (Duesseldorf / DE)
Antiviral therapy and resistance, Viral pathogenesis and persistence
Poster
P 059
Assay development for high-throughput antiviral compound screening against bunyavirus L protein
Dr. Dominik Vogel (Hamburg / DE)
Janna Scherf (Hamburg / DE)
Dr. Maria Rosenthal (Hamburg / DE)
Antiviral therapy and resistance, Viral replication strategies 1 (RNA viruses)
Poster
P 060
Ligand-based discovery of coronavirus main protease inhibitors using MACAW molecular embeddings
Dr. Mihayl Varbanov (Vandoeuvre les Nancy / FR)
Antiviral therapy and resistance, SARS-CoV-2
Poster
P 061
Enhancing antiviral immunity by blocking SAMHD1 activity and targeting viral immune evasion
Aleksandra Mitric (Erlangen / DE)
Antiviral therapy and resistance, Innate immunity
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