ToxoDB: Tools for Genomic-Scale Data Exploration, Analysis, Integration and Discovery

Biomedical research is increasingly driven by Big Data: genome sequences & diversity data, all manner of multi-Omics datasets, etc. How can we effectively collect, store, maintain and integrate this information to ensure FAIR (Findable,Accessible, Interoperable, Reusable) data access, advancing biological understanding and defining targets for further study in the lab, field & clinic? The Eukaryotic Pathogen & Vector Genomics Resource (VEuPathDB.org) – including ToxoDB.org– provides a robust, sustainable data-mining resource, accessed by 1000s of researchers daily, and demonstrably expediting discovery & translational research on diverse eukaryotic microbes (fungi & protists). We will be available at Toxo XVII to demonstrate database functionality and discuss topics of community interest, e.g.:

accessing & interpreting information on genes, genomes, population diversity, comparative genomics, DNA/protein motifs, protein structures, interactomes, epigenetics, transcriptomes, proteomes, metabolomes, pathways, subcellular localization, phenotypic characterization, orthology-based functional inference, automated & curated annotation, etc strategies for integrating & interrogating diverse datasets … and analyzing & sharing the results obtained assessing & improving the quality and accuracy of available annotation … capturing expert knowledge from the community analyzing your own (or any public) datasets via the free, private, easy-to-use, cloud-based VEuPathDB Galaxy instance … and integrating/querying results in the context of other data in FungiDB identification and prioritization of new Toxoplasma datasets for integration, and development of new database features; prospects for sustainable coordination with other resources new datasets & functionalities currently under development at VEuPathDB/FungiDB … what to expect over the coming years additional help & assistance with database mining & FAIR data access/sharing