18th European Headache Congress

Pathophysiological mechanisms of craniofacial pain, from bench to bedside

Doctor, my head hurts... This is the beginning of many clinical stories. This session aims to help the attendees to better understand the clinical work-up of craniofacial pain. This journey will begin with a review of the pathophysiology, will go through the clinical and diagnostic aspects, and will end up with the current and future treatment options.&lt;br&gt;&lt;ul&gt;&lt;li&gt;&lt;strong&gt; 1.	Pathophysiological mechanisms of craniofacial pain, from bench to bedside.&lt;/strong&gt;&lt;p&gt;Knowledge about the structures and pathways that are involved in craniofacial pain has significantly increased. This session will review the involved neuropeptides and the mechanisms implicated in the genesis, and perpetuation of pain. Preclinical and clinical models will be premanted and will be used to illustrate some craniofacial painful conditions.&lt;/p&gt;&lt;/li&gt;&lt;li&gt;&lt;strong&gt;2.	Diagnosis of typical and atypical craniofacial pain conditions&lt;/strong&gt;&lt;p&gt;Differential diagnosis of craniofacial pain is not an easy peasy. Multiple secondary causes may manifest as craniofacial pain, and when these are properly ruled out, several primary headache disorders should be considered. The pearls and pitfalls of the clinical diagnosis, and the diagnostic work-up will be revisited in this session.&lt;/p&gt; &lt;li&gt;&lt;strong&gt;3. Update on novel targets for craniofacial pain&lt;/strong&gt;&lt;/li&gt;&lt;p&gt;A lot is going on regarding the treatment of migraine, however, other primary and secondary headache disorders matter too. This session will review the existing treatment options for these headache disorders. All the prospect therapies that are currently under development and that may join the treatment armamentarium in the near future.&lt;/p&gt;

Eloisa Rubio-Beltran

Invited speaker