Simone Giudici (Rozzano / IT), Ezio Lanza (Rozzano / IT), Giulia Mauri (Rozzano / IT), Ludovica Lofino (Rozzano / IT), Alberto Barison (Rozzano / IT), Angela Ammirabile (Rozzano / IT), Martina Ceolin (Rozzano / IT), Francesca Margherita Bunino (Rozzano / IT), Davide Zulian (Rozzano / IT), Bruno Branciforte (Rozzano / IT), Antonella Ardito (Rozzano / IT), Simona Mei (Rozzano / IT), Andrea Brocchi (Rozzano / IT), Daniele Del Fabbro (Rozzano / IT)
Abstract text (incl. references and figure legends)
I
Emergency laparotomy (EL) is related to a high risk of morbidity and mortality. Low skeletal muscle mass (sarcopenia) and poor muscle quality (myosteatosis) have been reported as a prognostic predictor in various conditions. The impact of sarcopenia and myosteatosis on postoperative outcomes in patients who underwent emergency laparotomy were investigated.
M&M
A total of 242 consecutive patients who underwent emergency laparotomy from January 2015 to December 2021 were retrospectively evaluated. Skeletal muscle index (SMI) and Muscle Radiation Attenuation (MRA) was measured as the cross‐sectional area (cm2) of skeletal muscle in the L3 region on computed tomography (CT). SMI was normalized for height (cm2/m2). Sarcopenia was defined as an SMI of ≤41.6 and ≤ 32 cm2/m2 in men and women, respectively. Myosteatosis was defined as an MRA of ≤29.3 and ≤ 22 HU in men and women, respectively. Postoperative morbidity, mortality at 30 days, and length of hospital (LOS) stay were evaluated.
R
One hundred and eighteen were women, while 124 were men. Median age was 70 (range 21-96). One hundred and three patients were sarcopenics and 189 were myosteatosics, while 75 presented both characteristics. No differences were shown between sarcopenia and postoperative complications (Clavien Dindo>2), mortality at 30 days, and LOS. Myosteatosis, instead, was found to be associated with higher LOS (17 days versus 8 days, P 0.002) and higher severe complications rate (84,4% versus 14,6% P=0.0049) but not to 30 days mortality.
C
Myosteatosis, but not sarcopenia, seems to be related with increased adverse outcomes following emergency laparotomies. It would be useful to consider the myosteatosis, in addition to other clinical factors, to estimate the perioperative risk of patients candidate to emergency laparotomies.
R Park B Short-and long-term impact of sarcopenia on outcomes after emergency laparotomy:A systematic review and meta-analysis.Surgery.2022 Jul;172(1):436-445.
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