.css-1xsl8rf{width:100%;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;position:relative;overflow:hidden;background:var(--alert-bg);-webkit-padding-start:var(--chakra-space-4);padding-inline-start:var(--chakra-space-4);-webkit-padding-end:var(--chakra-space-4);padding-inline-end:var(--chakra-space-4);padding-top:var(--chakra-space-1);padding-bottom:var(--chakra-space-1);--alert-fg:var(--chakra-colors-orange-600);--alert-bg:var(--chakra-colors-orange-100);font-weight:var(--chakra-fontWeights-semibold);padding-left:var(--chakra-space-4);}.chakra-ui-dark .css-1xsl8rf:not([data-theme]),[data-theme=dark] .css-1xsl8rf:not([data-theme]),.css-1xsl8rf[data-theme=dark]{--alert-fg:var(--chakra-colors-orange-200);--alert-bg:rgba(251, 211, 141, 0.16);}@media screen and (min-width: 48em){.css-1xsl8rf{padding-left:var(--chakra-space-8);}}Please enable Javascript to use all features and improve your user experience.

Poster

Poster
Session 2

Appointment

Date: 08/03/2023

Time: 12:45 – 13:45

Location / Stream:

Foyer

Description

Posters will be presented during the time period mentioned above. This will give all participants and the poster jury the opportunity to interact with the presenting authors. Please be available to answer questions at your poster during the poster session.

Programme

Poster
P097
Impact of a conventional spasmolytic on the quality of life in patients with menstrual pain - Real world evidence data from a pharmacy-based patient survey
Pia Nonnenmacher (Frankfurt / DE)
Pharmacoepidemiology and drug safety
Poster
P098
What onset of pain relief corresponds to patients' assessment of "very fast" or "fast" in acute headache treatment? Analysis of data from an observational study on the fixed-dose combination ibuprofen+caffeine
Thomas Weiser (Frankfurt / DE)
Pharmacoepidemiology and drug safety
Poster
P099
Which parameters affect pain reduction in acute headache treatment? Analysis of data from an observational study on the fixed-dose combination ibuprofen+caffeine
Thomas Weiser (Frankfurt / DE)
Pharmacoepidemiology and drug safety
Poster
P100
Comprehensibility and clinical relevance of absolute contraindications – the perspective of German pharmacists and physicians
Wahram Andrikyan (Erlangen / DE)
Pharmacoepidemiology and drug safety , Pharmacological education
Poster
P101
Analysis of drug drug interactions between somatic and psychiatric medication by application of ABDA interaction data to reports from the EudraVigilance database
Catharina Scholl (Bonn / DE)
Pharmacoepidemiology and drug safety , Pharmacological education
Poster
P102
A descriptive analysis of medication errors reported in Vigibase for direct oral anticoagulants
Claudiu Morgovan (Sibiu / RO)
Cardiac pharmacology, Pharmacoepidemiology and drug safety
Poster
P103
Development of a smartphone-application enabling personalized selection of suitable food products in consideration of drug intake, food intolerances and allergies: opportunities and limitations
Daniela Pemp (Würzburg / DE)
Pharmacoepidemiology and drug safety
Poster
P104
A descriptive study of adverse drug reactions relevant to antimicrobial resistance reported for azole antifungals
Anca Arseniu (Sibiu / RO)
Claudiu Morgovan (Sibiu / RO)
Immunopharmacology / inflammation / anti-infectives , Pharmacoepidemiology and drug safety
Poster
P105
Patient risk profiles in polytherapy: Patient-reported safety outcome measures, potentially inadequate medication (PIM) and drug-drug-interactions in an elderly cohort, a longitudinal investigation
Jason-Christopher Radermacher (Aachen / DE)
Pharmacoepidemiology and drug safety
Poster
P106
Gene-environment interactions and interindividual variability in xenobiotic response – a genome-wide association study in medaka
Philip Watson (Heidelberg / DE)
Drug transport/delivery and metabolism, Pharmacogenomics and personalized medicine
Poster
P107
Influence of the single nucleotide polymorphisms rs12252 and rs34481144 in IFITM3 on humoral immune response after vaccination against COVID-19
Ieva Ciuciulkaite (Essen / DE)
Immunopharmacology / inflammation / anti-infectives , Pharmacogenomics and personalized medicine
Poster
P108
Characterization of the EMPAR cohort – Health care claims data and CYP2D6 profiles
Tatjana Huebner (Bonn / DE)
Pharmacoepidemiology and drug safety , Pharmacogenomics and personalized medicine
Poster
P109
A comparison of pharmacogenomic raw genotyping data from DTC-GT services and third-party interpretation websites with conventional laboratory testing
Jérôme Bonzon (Zürich / CH)
Enrico Stefano Maria Ermanni (Zürich / CH)
Pharmacoepidemiology and drug safety , Pharmacogenomics and personalized medicine
Poster
P110
Detection of bladder cancer specific mutations in human tissue and urine samples by mass spectrometry
Nina Reichelt (Bochum / DE)
Genotixicity and carcinogenesis , Pharmacogenomics and personalized medicine
Poster
P111
Targeted investigation of prenyltransferase promoters shows no aberrant DNA methylation in cancer cells, but reveals evidence for differential, CpG-site-specific maximum proportion of DNA methylation independent of cell line, chromatin state and methylation mechanism.
Dominik Jung (Witten / DE)
Cancer pharmacology , Pharmacogenomics and personalized medicine
Poster
P112
PharmFreq: a comprehensive database of worldwide allelic frequencies in clinically important pharmacogenes
Roman Tremmel (Stuttgart / DE)
Pharmacoepidemiology and drug safety , Pharmacogenomics and personalized medicine
Poster
P113
Assessment of circulating metabolites reveals isobutyrate and propionate associated with lean NAFLD: consequences on steatosis prediction and lipid accumulation
Mathias Haag (Stuttgart / DE)
Disease models, drug development, Pharmacogenomics and personalized medicine
Poster
P114
Multi-dimensional omics profiling of a biobank reveals the interindividual variability of ADME gene expression in human liver
Kathrin Klein (Stuttgart / DE)
Nuclear receptors, enzymes and other targets , Pharmacogenomics and personalized medicine
Poster
P115
"RNA-Analytics via Microscale Thermophoresis (MST) - A tool to study molecular interactions in solution"
Markus Herkt (Hannover / DE)
Drug transport/delivery and metabolism, Pharmacokinetics and PK/PD modelling
Poster
P116
Workflow proposal for setting upper concentrations in in vitro toxicity testing
Robert Landsiedel (Ludwigshafen am Rhein / DE)
Pharmacokinetics and PK/PD modelling , Toxicological methods and in vitro toxicology
Poster
P117
Effect of aging on the pharmacokinetics of metformin, penicillin, sumatriptan, and metoprolol in rats
Mladen V. Tzvetkov (Greifswald / DE)
Drug transport/delivery and metabolism, Pharmacokinetics and PK/PD modelling
Poster
P118
Determination of Respiratory Pharmacokinetic Parameters using a Combination of Physiologically Based Pharmacokinetic Modelling and an Isolated Perfused Lung Model
Katharina Schwarz (Hannover / DE)
Drug transport/delivery and metabolism, Pharmacokinetics and PK/PD modelling
Poster
P119
GENE EXPRESSION AND PROTEIN ABUNDANCE OF MINOR DRUG METABOLIZING ENZYMES IN HUMAN INTESTINE AND LIVER: AN INTER- AND INTRA-SUBJECT ANALYSIS
Stefan Oswald (Rostock / DE)
Drug transport/delivery and metabolism, Pharmacokinetics and PK/PD modelling
Poster
P121
Desorption/ionization mass spectrometric methods for drug quantification in biological matrices and their validation following regulatory guidance.
Rémi Longuespée (Heidelberg / DE)
Pharmacokinetics and PK/PD modelling
Poster
P122
PubPharm's tools for advanced searches: Generating structured drug overviews from literature
Stefan Wulle (Braunschweig / DE)
Pharmacological education, Toxicological education
Poster
P123
Alpha-adrenergic receptors in clinical practice – Present and future
Patrick Lechsner (Targu Mures / RO)
G-protein coupled receptors
Poster
P124
Innovative online toxicology teaching: ToxLearn4EU, an Erasmus international project
Helga Stopper (Würzburg / DE)
Toxic compounds, Toxicological education
Poster
P125
Updates in legislation and advice for read-across in REACH
Jochen vom Brocke (Helsinki / FI)
Toxicological education, Toxicological methods and in vitro toxicology
Poster
P126
Assessment of metabolic perturbation by Novaluron in the context of endocrine disruption
Anne Schmitt (Berlin / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P127
Assessment of the performance of a New Approach Method (NAM) testing DIO1 inhibition using a human microsome based, colorimetric assay
Nina Hambruch (Ludwigshafen am Rhein / DE)
Nuclear receptors, enzymes and other targets , Toxicological methods and in vitro toxicology
Poster
P128
Development of novel techniques advanced by bioinformatics methods for the characterization of biogenic toxins
Danny Kaser (Potsdam / DE)
Toxicological methods and in vitro toxicology, Toxins
Poster
P129
AI tools and methods for screening, extracting and evaluating NAM data for chemical risk assessment
Tilmann Blümmel (Frankfurt am Main / DE)
Florian Padberg (Berlin / DE)
Food toxicology , Toxicological methods and in vitro toxicology
Poster
P130
hiPSCs and hiPSCs-derived renal proximal tubular cells showed different response to nephrotoxic compounds
Isaac Musong Mboni Johnston (Düsseldorf / DE)
Toxicological methods and in vitro toxicology
Poster
P131
Stem cell-derived alveolar epithelial cells as promising lung cell source for preclinical drug testing and toxicity screening
Michelle Müller (Sulzbach / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P132
Suffocation through strong agglomeration of particles in the nose of test animals – new approaches for acute high dose inhalation studies that only consider animal survival
Gustav Bruer (Hannover / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P133
Suitability of precision cut kidney slices for the detection of nephrotoxic effects
Frauke Roolfs (Düsseldorf / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P134
Precision cut liver slices for 3R-conform assessment of hepatotoxicity
Ahmed Erbay (Düsseldorf / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P135
Influence of Nephrotoxins on the Differentiation Process of Human Induced Pluripotent Stem Cells (hiPSCs) into Proximal Tubular Epithelial Like Cells (PTELCs)
Nazih Mohamed Zakari Kouidrat (Düsseldorf / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P136
Opportunities and challenges of an imaging-based cell-cycle assay (CCA) for screening approach of chemicals
Barbara Birk
Disease models, drug development, Toxicological methods and in vitro toxicology
Poster
P137
Comparison of grouping of phenoxy herbicides with metabolomics in vitro and in vivo
Franziska Zickgraf (Ludwigshafen am Rhein / DE)
Toxicological methods and in vitro toxicology
Poster
P138
A novel primary cell airway model from the porcine trachea for the development and screening of inhalative drugs and their formulations
Rebecca Rittersberger (Biberach an der Riß / DE)
Drug transport/delivery and metabolism, Toxicological methods and in vitro toxicology
Poster
P139
Ferroptosis after sulfur mustard exposure
Tobias Demel (München / DE)
Toxic compounds, Toxicological methods and in vitro toxicology
Poster
P140
Development of RNA-based risk assessments for cardiotoxicity in rat cardiomyoblasts and living myocardial slices
Anna-Leena Kassandra Heim (Hannover / DE)
Drug transport/delivery and metabolism, Toxicological methods and in vitro toxicology
Poster
P141
Different geometry of diffusion cells and its impact on cutaneous penetration of Caffeine in vitro
Natascha Schmieder (Ludwigshafen / DE)
Biotransformation and toxicokinetics , Toxicological methods and in vitro toxicology
Poster
P142
Influence of drug candidates on sulfur mustard induced senescence in human mesenchymal stem cells
Adrian Neu (Munich / DE)
Toxic compounds, Toxicological methods and in vitro toxicology
Poster
P143
Melanin Nanoparticles as Novel Approach in Malignant Melanoma Treatment – An In Vitro Assessment
Iasmina Marcovici (Timisoara / RO)
Nanomaterials, Toxicological methods and in vitro toxicology
Poster
P144
Investigating the effect of Novaluron on HepaRG cells
Sreejita Das (BERLIN / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P145
Characteristics of dusts from recycling of carbon fiber reinforced thermoplastics (CFRP) and their toxic potential
Götz Westphal (Bochum / DE)
Toxicological methods and in vitro toxicology, Toxins
Poster
P146
Assessing the direct effect of antibiotics on mitochondrial respiration
Judith Sailer (München / DE)
Toxic compounds, Toxicological methods and in vitro toxicology
Poster
P147
An LC-MS method to study displacement of thyroid hormones from serum proteins by test substances.
Luisa Jedermann (Ludwigshafen am Rhein / DE)
CNS / endocrine pharmacology, Toxicological methods and in vitro toxicology
Poster
P148
Cyp activities in a monolayer culture of primary mouse hepatocytes cultivated for five days
Matthias Scherer (Ludwigshafen am Rhein / DE)
Nuclear receptors, enzymes and other targets , Toxicological methods and in vitro toxicology
Poster
P149
Frequencies and TCR repertoires of human metal-specific CD4+ T cells
Franziska Riedel (Berlin / DE)
Toxicological methods and in vitro toxicology
Poster
P150
Phenotypic anchoring for OMICS-guided assessment of liver toxicity in zebrafish
Gaëlle Hayot (Eggenstein-Leopoldshafen / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P151
Quantitative and qualitative assessment of cytotoxicity by automated fluorescence microscopy in human hepatocytes
Christina Alexandra Cramer von Clausbruch (Eggenstein-Leopoldshafen / DE)
Organ toxicology , Toxicological methods and in vitro toxicology
Poster
P152
Study on the contribution of adjuvants on the sensitising potential of plant protection products using in vitro experiments
Denise Bloch (Berlin / DE)
Toxic compounds, Toxicological methods and in vitro toxicology
Poster
P153
Label-free quantitative proteomics on human bronchial epithelial cell proteome after cadmium exposure
Martin Link (Karlsruhe / DE)
Genotixicity and carcinogenesis , Toxicological methods and in vitro toxicology
Poster
P154
New approach methods for the identification of skin allergens
Kerstin Egele (Trier / DE)
Toxic compounds, Toxicological methods and in vitro toxicology
Poster
P155
The in vitro biological activity of probiotics combination on human colorectal carcinoma cells
Alina Anton (Timisoara / RO)
Cancer pharmacology , Toxicological methods and in vitro toxicology
Poster
P156
Cytotoxicity assessment of Galium verum extracts on human melanoma cells
Alexandra Denisa Semenescu (Timisoara / RO)
Cancer pharmacology , Toxicological methods and in vitro toxicology
Poster
P157
Oleanolic acid encapsulated in liposomes as a potential therapeutic approach for hepatocellular carcinoma
Ioana Macașoi (Timisoara / RO)
Nuclear receptors, enzymes and other targets , Toxicological methods and in vitro toxicology
Poster
P159
Mutational analyses of proteinaceous toxins using cell-free systems
Franziska Ramm (Potsdam / DE)
Toxicological methods and in vitro toxicology, Toxins
Poster
P160
Revising sulfated glucosminoglycans as receptors for C. difficile TcdA reveals a minor role in uptake of toxin
Ralf Gerhard (Hannover / DE)
Toxins
Poster
P161
Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin in different ways
Carolin Kling (Ulm / DE)
Disease models, drug development, Toxins
Poster
P162
Chlamydia muridarum TC0438 - a new DxD-motif harbouring chlamydial cytotoxin
Harald Genth (Hannover / DE)
Signal transduction and second messengers , Toxins
Poster
P163
Simultaneous Detection, Differentiation and Quantification of Eight Staphylococcal Enterotoxins in a Multiplex Suspension Assay
Paulin Dettmann (Berlin / DE)
Food toxicology , Toxins
Poster
P164
Multifunctional peptide nanocarrier for targeted pharmacological modulation of metastatic breast cancer cell proliferation and osteolysis in the bone microenvironment
Nicole Stadler (Ulm / DE)
Toxins
Poster
P165
Evaluation of the in vitro neutralizing capacity of anti-ricin antibodies
Amina El Houari (Berlin / DE)
Toxic compounds, Toxins
Poster
P166
Characterization of GPR4 antagonists using FRET-based GPR4 reporter cell lines
Frank Wunder (Wuppertal / DE)
G-protein coupled receptors, Signal transduction and second messengers
Poster
P167
The Membrane Palmitoylated Protein 1 (MPP1) Induces Angiotensin II AT1 Receptor (AGTR1) Sensitization in Vitro and Features of Heart Failure in Vivo
Eric Nerger (Zurich / CH)
Cardiac pharmacology, G-protein coupled receptors
Poster
P168
Metabolic and cellular factors determining the therapeutic effect of dimethyl fumarate
Joanna Kosinska (Lübeck / DE)
Disease models, drug development, G-protein coupled receptors
Poster
P169
Signature of cannabinoid receptor phosphorylation in vitro and in vivo
Andrea Kliewer (Jena / DE)
G-protein coupled receptors
Poster
P170
Relaxin receptor RXFP1 is targeted by novel interaction partners CTRP1, CTRP6 and CTRP8 in corneal wound healing
Hagen Fabian Nicolaus (Erlangen / DE)
G-protein coupled receptors, Signal transduction and second messengers
Poster
P171
Role of Ubiquitination for co-internalization of arrestin3 with G protein coupled receptors
Sebastian Ernst (Marburg / DE)
G-protein coupled receptors, Signal transduction and second messengers
Poster
P172
FRET-based neurotensin 1 receptor conformation sensor to study on- and off-kinetics in intact cells and under cell-free conditions
Uurtuya Hochban (Marburg / DE)
G-protein coupled receptors
Poster
P173
Agonist affinity of prostanoid receptor sensors decreases in non-intact cells
Michael Kurz (Marburg / DE)
G-protein coupled receptors, Immunopharmacology / inflammation / anti-infectives
Poster
P174
Human DP2 receptor based FRET conformation sensor gives new insights into pharmacology and reveals arachidonic acid to be a partial agonist DP2 receptor
Michaela Ulrich (Marburg / DE)
G-protein coupled receptors, Signal transduction and second messengers
Poster
P175
Mode and sites of action of ligands activating the human GPR84-receptor
Sujeepan Pannerselvam (Bonn / DE)
G-protein coupled receptors, Immunopharmacology / inflammation / anti-infectives
Poster
P176
A novel CDK12 "degrader" time and dose-dependently suppresses NF-κB signaling
Jasmin Priester (Gießen / DE)
Cancer pharmacology , Immunopharmacology / inflammation / anti-infectives
Poster
P177
The role of autophagy and the related ER-phagy in coronavirus infected cells
Franziska Maria Dort (Gießen / DE)
Immunopharmacology / inflammation / anti-infectives , Signal transduction and second messengers
Poster
P178
CRISPR/Cas9-based activation and depletion of individual cytokine genes
Helke Peppler (Giessen / DE)
Immunopharmacology / inflammation / anti-infectives , Signal transduction and second messengers
Poster
P179
Analysis of global RNA and protein biosynthesis in response to interleukin-1 by a metabolic labelling approach
Simon Hanel (Giessen / DE)
Immunopharmacology / inflammation / anti-infectives , Toxicological methods and in vitro toxicology
Poster
P181
ANG – a critical factor in pathological aging and Alzheimer's disease?
Marko Joerg (Mainz / DE)
Disease models, drug development, Nuclear receptors, enzymes and other targets
Poster
P182
The role of RNA modification m¹A in Alzheimer"s Disease.
Marko Joerg (Mainz / DE)
Christine Lietz (Mainz / DE)
Disease models, drug development, Nuclear receptors, enzymes and other targets
Poster
P183
Effects of farnesyltransferase inhibitors on matrix-vesicle mediated mineralization in osteosarcoma cells
Tim Bürgel (Witten / DE)
Cancer pharmacology , Nuclear receptors, enzymes and other targets
Poster
P184
Pharmacological characterization of the interaction between human farnesyltransferase variants with the proto-oncogene Ras
Jessica Jasmin Schott (Witten / DE)
Cancer pharmacology , Nuclear receptors, enzymes and other targets
Poster
P185
Metabolic effects of Cimicfuga racemosa extract Ze 450 on mitochondria and implications for the resistance against oxidative cell death
Madeline Günther (Marburg / DE)
Disease models, drug development, Nuclear receptors, enzymes and other targets
Poster
P186
Relevance of Rac1 in doxorubicin-induced cytotoxicity in different primary cardiac cell types
Pelin Kucuk (Düsseldorf / DE)
Cardiac pharmacology, Signal transduction and second messengers
Poster
P187
PP2A-PR72 improves contractile function of cardiomyocytes
Julius Roman Herting (Münster / DE)
Jule Hannah König (Münster / DE)
Cardiac pharmacology, Signal transduction and second messengers
Poster
P188
Enhanced cAMP level and cAMP-dependent transcription in human induced pluripotent stem cell derived atrial cardiomyocytes with Annexin A4 knockout
Jan Schmidt (Münster / DE)
G-protein coupled receptors, Signal transduction and second messengers
Poster
P189
cNMPs as potential therapeutics for various human carcinoma cell lines
Sabine Wolter (Hannover / DE)
Cancer pharmacology , Signal transduction and second messengers
Poster
P190
Identification of constituents conveying signals from MYD88L265P and CXCR4 or CXCR4-WHIM mutants leading to enhanced malignancy of Waldenstrom macroglobulinemia
Lobna Abdella (Ulm / DE)
Immunopharmacology / inflammation / anti-infectives , Signal transduction and second messengers
Poster
P191
Plexins are required for epithelial regeneration
Dandan Zhao (Marburg / DE)
Disease models, drug development, Signal transduction and second messengers
Poster
P192
Development of a cUMP-specific BRET sensor
Bastian Schirmer (Hannover / DE)
Signal transduction and second messengers , Toxins
Poster
P193
Role of Phosphatase and Tensin homolog (Pten) in Insulin mediated DNA damage
Ezgi Eylül Bankoglu (Würzburg / DE)
Genotixicity and carcinogenesis

PosterSession 2

Appointment

Description

Programme

Poster
Session 2