8th German Pharm-Tox Summit

Long non-coding RNA-mediated control of the cardiac rhythm

Cardiac pharmacology

<B>Posters will be presented during the time period mentioned above. This will give all participants and the poster jury the opportunity to interact with the presenting authors. Please be available to answer questions at your poster during the poster session.  

Session 1

Poster

Disease models, drug development

microRNA-21 inhibition prevents adverse cardiac remodeling and dysfunction following myocardial infarction, an effect driven by macrophages.

Cardiac pharmacology and treatment

Oral presentation

Immunopharmacology / inflammation / anti-infectives	

Topical application of inhaled macrophage-specific carbohydrate-coupled antimiR-21 attenuates pulmonary inflammation and fibrosis – two hallmarks of COVID-19.

Drug transport/delivery and metabolism

In vivo microRNA activity sensing of the mammalian heart at single-cell resolution reveals selective uptake of antisense oligonucleotides by injured cardiomyocytes

Prof. Dr. Dr.

Stefan Engelhardt

Further involvements