8th German Pharm-Tox Summit

Assessment of the performance of a New Approach Method (NAM) testing DIO1 inhibition using a human microsome based, colorimetric assay

Toxicological methods and in vitro toxicology

Posters will be presented during the time period mentioned above. This will give all participants and the poster jury the opportunity to interact with the presenting authors. Please be available to answer questions at your poster during the poster session.

Session 2

Poster

Nuclear receptors, enzymes and other targets		

Opportunities and challenges of an imaging-based cell-cycle assay (CCA) for screening approach of chemicals

Disease models, drug development

Comparison of grouping of phenoxy herbicides with metabolomics in vitro and in vivo

Different geometry of diffusion cells and its impact on cutaneous penetration of Caffeine in vitro

Biotransformation and toxicokinetics	

Workflow proposal for setting upper concentrations in in vitro toxicity testing

Pharmacokinetics and PK/PD modelling	

Assessment of the Mutagenic Potential of a Protoporphyrinogen-Oxidase Inhibitor Herbicide

Genotixicity and carcinogenesis	

Posters will be presented during the time period mentioned above. This will give all participants and the poster jury the opportunity to interact with the presenting authors. Please be available to answer questions at your poster during the poster session.

Session 1

An LC-MS method to study displacement of thyroid hormones from serum proteins by test substances.

CNS / endocrine pharmacology

Cyp activities in a monolayer culture of primary mouse hepatocytes cultivated for five days

Dorothee Funk Weyer

Further involvements