Die Hemmung der Protein Tyrosin Phosphatase PTP1B mittels dem small molecule Claramine inhibiert die EGF-vermittelte Wachstumssteigerung in Glioblastozellen durch Hemmung des MAPK Signalwegs

Inhibition of the protein tyrosine phosphatase PTP1B by the small molecule inhibitor claramine inhibits growth stimulation by EGF in glioblastoma cells via inhibition of the MAPK pathway