Hypoglossus nerv Stimulation als Alternative in der Therapie der Obstructiven Schlafapnoe

Due to the very poor therapy acceptance and the side effects of CPAP therapy in obstructive sleep apnea, there is a great need for alternatives. Hypoglossal stimulation represents a new therapy option that has been available since 2016. In this study, we would like to present our initial results from 53 patients with implanted hypoglossal stimulators.

In the period from August 2016 to December 2023, we were able to evaluate the data from 52 patients with respiratory sensor-triggered hypoglossal stimulators that were implanted by us. The pre- and postoperative AHI was determined using polygraphy and polysomnography, the pre- and postoperative daytime sleepiness using the Epworth Sleepiness Scale (ESS) and patient satisfaction were determined.

In 48 out of 52 patients (92.3%), we observed a reduction in AHI under stimulation by over 60%. Four patients did not tolerate this therapy or did not use it regularly. Twenty-six patients (47.3%) achieved a reduction in AHI of over 80% from the baseline value. Regarding daytime sleepiness, there was an average reduction in the ESS score from 10 to 6.5. The subjectively reported satisfaction with sleep improved by 66.3% in 43 evaluable patients.

Stimulating the hypoglossal nerve for the treatment of OSA (obstructive sleep apnea) provides a viable alternative to CPAP/PAP therapy. With strict indications, an acceptable reduction in AHI (apnea-hypopnea index) can be achieved. Daytime sleepiness is effectively treated, and the subjectively perceived sleep quality improves. This is a new and emerging technology with the potential to replace PAP therapy in the coming years.