Longitudinal in vivo 2-Photon microscopy via an implanted spinal window chamber is feasible up to the chronic phase following experimental spinal cord injury in the mouse.
The partial recovery of the integrity of the neurovascular unit is associated with functional recovery after experimental spinal cord injury in the mouse.
Posttraumatic disruption of the blood-spinal-cord-barrier in the acute phase is aggravated by the endothelial cell-specific knock-out of Ephrin-B2 signaling after experimental spinal cord injury.