Microsymposium 12
Bio-Crystallography IV: Structure-based design

Programme

• 09:00 – 09:20 16 Min. 4 Min.

  • Short talk
  • OP-052

  Structural characterization of WDR5-degrader interfaces and its implications for optimal PROTAC design

  • Andreas Kraemer (Frankfurt am Main / DE)

   Bio-Crystallography I: Signaling, macromolecular interactions and new structures, Bio-Crystallography III: Structure-based design
• 09:20 – 09:50 25 Min. 5 Min.

  • Keynote lecture
  • OP-053

  Structural elucidation of cathepsin L inhibitors is pushing the concept of dual-target anti-viral drugs

  • Sven Falke (Hamburg / DE)

   Bio-Crystallography I: Signaling, macromolecular interactions and new structures, Bio-Crystallography IV: Synchrotrons and high throughput methods
• 09:50 – 10:10 16 Min. 4 Min.

  • Short talk
  • OP-054

  The induced-fit binding mechanism of cell-permeable dichlorophenylpyridine-based furin inhibitors

  • Sven O. Dahms (Salzburg / AT)

   Bio-Crystallography I: Signaling, macromolecular interactions and new structures, Bio-Crystallography III: Structure-based design
• 10:10 – 10:30 16 Min. 4 Min.

  • Short talk
  • OP-055

  Allosteric inhibition as a new mode of action: A neutralizing antibody targeting the activated form of coagulation factor XI

  • Martina Schaefer (Berlin / DE)

   Bio-Crystallography III: Structure-based design