Alicia Gonzalez-Martinez (Madrid/ ES), Paula Paños Basterra (Madrid/ ES), Marta Domínguez Gallego (Madrid/ ES), Alba Somovilla (Madrid/ ES), Carmen Martín Ramos (Madrid/ ES), Álvaro Morales Caballero (Madrid/ ES), Amparo López Guerrero (Madrid/ ES), Manuela García Cebrián (Madrid/ ES), José Vivancos (Madrid/ ES), Ana Beatriz Gago-Veiga (Madrid/ ES)
Abstract text (incl. figure legends and references)
Objective: Headache is a frequent symptom during SARS-CoV-2 infection and following COVID-19 immunization. We aimed to characterize the semiology of COVID-19 headache and COVID-19 immunization headache, as well as to evaluate the influence of primary headache-migraine or tension-type headache(TTH)-on the COVID-19 headache and COVID-19 immunization headache phenotype.
Methods: We performed an observational study through an online survey in healthcare workers who had SARS-CoV-2 infection and were included in the Occupational Medicine´s register of our tertiary hospital. Clinical, demographic and headache variables were collected during infection and immunization.
Results: We included 109 participants with COVID-19 headache, 94/109(86,2%) women, 45.1(SD:12.45 years, 24.1(SD:4.3) BMI, 29/109(26.6%) cardiovascular risk factors, 15/112(13.39%) 15/109(13.8%) anxiety, 7/109(6.4%) depression, 22/109(20.18%) migraine as primary headache, 11/109(10,09%) TTH as primary headache. COVID-19 headache was the first symptom in 24/109(22%), appeared in
Conclusions: According to our study, both COVID-19 headache and COVID-19 immunization headache frequently follow a TTH-like phenotype more than a migraine phenotype. Moreover, COVID-19 immunization headache is frequently more similar to the COVID-19 headache than to the primary headache.