Application of negative pressure wound therapy during chronic wound treatment in traumatology practice

Abstract text (incl. references and figure legends)

Background: Negative pressure wound therapy (NPWT) has become the golden standard regarding care of high risk, enlarged or chronic wounds within Traumatology. However, there is conflicting literature on its impact on infectious complications. Our aim was to compare the effects of NPWT and conventional treatment on wound complications after total endoprosthesis (TEP).

Materials and methods: Retrospective cohort study (e.sz.: 69/2019-SZTE). A total of 369 patients underwent TEP implantation with wound complication at the Traumatology Department from 2015 to 2022. The patients were divided into two groups, whether they received NPWT (n=64) or not (Control group, n=32). The primary outcome according to wound healing was healed, chronic wound and exitus. The secondary outcome measures included the number and the frequency of dressing change, lenght of antibiotic (Ab) treatment, and hospital stay.

Results: There was no difference in the number and the frequency of dressing change between groups. However, the 25 % of wounds in the NWPT group healed and 45 % of cases turned into chronic wounds, compared to the Control (41% and 42 %) The mortality rate was twice as high in the NWTH group and the lenght of hospital stay and Ab treatment was longer when compared to the Control group (8,97 days vs 6,08 days).

Conclusion: Based on the results, when NPWT therapy is utilized in appropriate amounts and quality, the results are good, However, not all facets of the study were proven true and further studies may be necessary to fully understand the method of NPWT.

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