57. Jahrestagung der Deutschen Gesellschaft für Transfusionsmedizin und Immunhämatologie

Prof. Dr. med.

Vorsitz

Dr. med.

Challenges to meet immunoglobulin demand now and in the future

MD PhD

Referent

Lecture

Donor Health Management research in the Netherlands: an overview and insights from a recent upper age limit increase

Professor

&quot;Pop-Up Blood Donation&quot; as a novel channel for potential young blood donors in urban areas –results from three first implementations

Blood Donation

"Pop-Up-Blutspende" als neuer Kanal für potenzielle Blutspender in städtischen Regionen – Ergebnisse der ersten drei Implementierungen

While the number of blood donors is decreasing, the average age of donors is increasing. Blood donors in our organization tend to live more in rural areas and have an average age above 45 years. Hence, given the demographic development, it is mandatory to develop new channels to attract younger blood donors and with a focus in urban areas. We opened three &quot;Pop-Up Blood Donation&quot; (PUBD)-sites in shopping malls to encourage spontaneous blood donation of a rather young and urban population.We gathered data from the three PUBD-sites since their individual opening on a daily basis. Data collected included age, sex, first-time vs. repeat donor, time since last donation (if applicable), distance residential to PUBD-adress, percentage of non-eligibility, etc. Data from the three PUBD-sites were compared to data from two permanent donation sites and two mobile donation opportunities in the past 365 days (&quot;other sites&quot;). Due to the short period of follow-up, solid conclusions regarding e.g. adherence of blood donors in the three PUBD-sites cannot be drawn at this moment. In the future, it is planned to apply artificial intelligence to predict e.g. adherence of blood donors acquired through the various blood donation channels.The PUBD-sites were opened in Dortmund (15.09.2023), Düsseldorf (01.11.2023) and Leverkusen (06.12.2023). The first-time donation rate is 33.0% in the PUBD compared to 5.2% in the other sites. The average age is 40.1 years in the PUBD compared to 50.5 years in the other sites. The PUBD-sites show a high &quot;reactiviation rate&quot; (20.8% vs. 10.5% in other sites), i.e. donors who had donated earlier in the past, but not during the past two years and donated now again. The distance of residence to donation site is higher in PUBD (median 7km) than in other donation sites (median 3km), since normally donors tend to donate in the vicinity of their residence. The rate of non-eligibility, however, is higher in the PUBD-sites (21.0% vs. 8.2%).&quot;Pop-Up Blood Donation&quot; (PUBD)-sites in city shopping malls may help to attract younger potential blood donors in urban areas who have never donated blood before. The hurdle to donate blood is lowered by enabling blood donation in a shopping mall and on a spontaneous basis. It is, however, to early to evaluate how many of these young first-time donors will turn into regular donors. PUBD-sites in shopping malls could help to activate a blood donor population not well accessed so far.There are no conflict of interests.

Abstract lecture

Prof. Dr.

Whole blood donation without an age limit: What we have learned so far

Vollblutspende ohne Altersgrenze: was wie bisher gelernt haben

Due to a change of the German drug law in 2023, the general upper age limit for blood donation was abolished and deferral or exclusion from blood donation in blood donors from ≥ 73 years (WBD≥73y) must now always be based on an individual decision. In order to continuously ensure the safety of elderly blood donors, a thorough investigation (Eignungsuntersuchung=EU) every 5 years from 60 years onwards has been implemented in return.Since the implementation in October 2023, a total of 591.842 whole blood donation (WBD) attempts either in fixed (68.023) or mobile (523.819) collection sites (FCS versus MCS) of the German Red Cross Blood Services Baden-Württemberg - Hessia (BWH) and Northeast (NE) have been analysed and the following parameters were determined focussing on WBD≥73y: number of donations, deferrals/exclusions, deferral rate, reasons for deferral, number of first time donors (FTD), number of local and systemic donor adverse events and number of EU in WBD≥60y.340/68.023 collection attempts at FCS and 2.238/523.819 at MCS were from donors ≥ 73 years, while 271/60.228 WBD at FCS and 1.906/485.200 WBD at MCS were from that age group resulting in a deferral rate of 20%. The oldest successful donor was 89 yrs. of age! Most frequent reasons for deferral/exclusion were: 1. elevated blood pressure, 2. cardiovascular diseases, 3. endoscopy. The overall FTD-rate in WBD≥73y was 154/2.578 (6.0%). Of 72 adverse events observed in 2.177 WBD (3.3%) 3 were systemic hypotonic reactions (1 requiring further treatment), whereas 69 were local reactions. Among 591.842 collection attempts in total, 6.257 (1.06%) required an EU as they were from WBD≥60y.Since the breaking up of the upper age limit, we collected 2.177 WBD from WBD≥73y equivalent to only 0.4% of all collected WBD. Even though the majority were former WBD, we observed a 6.0% FTD-rate among this cohort. The overall deferral rate of 20% is comparable to FTD and most common reasons were mainly due cardiovascular disease. As the 3.3%-rate of adverse events was not elevated, we conclude that WBD from WBD≥73y can be regarded safe. However, ongoing analysis is required to ensure that the safety of WBD≥73y can be warranted.none

Raum 27

Donor Management

Sektionssitzungen

Donor Management

Termin

Vorsitz

Sprache

Programm