8th German Pharm-Tox Summit

Effects of farnesyltransferase inhibitors on matrix-vesicle mediated mineralization in osteosarcoma cells

Nuclear receptors, enzymes and other targets		

<B>Posters will be presented during the time period mentioned above. This will give all participants and the poster jury the opportunity to interact with the presenting authors. Please be available to answer questions at your poster during the poster session. </B>


Session 2

Poster

Cancer pharmacology	

Bactericidal potential of drugs targeting the mevalonate pathway

Disease models, drug development

<B>Posters will be presented during the time period mentioned above. This will give all participants and the poster jury the opportunity to interact with the presenting authors. Please be available to answer questions at your poster during the poster session.  

Session 1

Immunopharmacology / inflammation / anti-infectives	

Targeted investigation of prenyltransferase promoters shows no aberrant DNA methylation in cancer cells, but reveals evidence for differential, CpG-site-specific maximum proportion of DNA methylation independent of cell line, chromatin state and methylation mechanism.

Pharmacogenomics and personalized medicine	

Pharmacological characterization of the interaction between human farnesyltransferase variants with the proto-oncogene Ras

Prof. Dr.

Hagen Sjard Bachmann

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