Role of Platelet Rich Plasma in improving quality of life in patients with atrophic rhinitis

Background: An atrophy of the nasal mucosa, gradual atrophy of the turbinate's supporting bone, excessive enlargement of the nasal chambers, sticky secretion, and dry crusts that form a peculiar fetor are all characteristics of atrophic rhinitis (AR), a chronic debilitating nasal mucosal condition.

Aim: to evaluate the effectiveness of PRP in improving the quality of life in patients with atrophic rhinitis.

Methods: Thirty patients with primary atrophic rhinitis attended the ENT outpatient clinics of the Fayoum University Hospital within 18 months. They were divided into two equal groups (A and B) each group consists of 15 patients.

Results: The PRP group showed a statistically significant difference between the initial score and scores at 1,2,3, and 6 months, as the mean initial score was 22.4 (SD=3.0), while the mean SNOT 25 score after 1 month was 22.2 (SD=3.2) after 2 months was 17.9 (SD=2.9) after 3 months was 15.3 (SD=3.8), and finally after 6 months was 12.7 (SD=4.9), p-value

Conclusion: Through autologous PRP injection, this study offered a novel regenerative approach for atrophic rhinitis treatment that can help atrophic rhinitis patients.

Keywords: atrophic rhinitis, allergic rhinitis, platelet-rich plasma, and PRP

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