95. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie

Prof. Dr.

Chairs

Prof. Dr. 

NUR Wissenschaftliches Programm/ ONLY Scientific Program

Drug-induced Sleep Endoscopy is Useful to Improve Treatment Outcome

Invited lecture

Myofunctional Therapy for Obstructive Sleep Apnoea – Myth or Reality?

International Variations in Surgical Treatment Approach to OSA Patients

MD, PhD

Hypoglossal Nerve Stimulation as Primary Treatment or only in Surgical Failures?

What to Do in Difficult Hypoglossal Nerve Stimulation Cases?

Impact of respiration synchronized hypoglossal nerve stimulation on pupillographic sleepiness test results

Auswirkung des atmungssynchronen Hypoglossusstimulators auf die Ergebnisse des pupillographischen Schläfrigkeitstests

Introduction:The pupillographic sleepiness test (PST) assesses the tonic central nervous activation. Its results are an accurate predictor of alertness and performance across daytime sleepiness. We investigated the effectiveness of the therapy with a respiration synchronized hypoglossal nerve stimulator (Inspire Upper Airway Stimulation, UAS) regarding daytime sleepiness with respect to the tonic activation. Methods:We conducted a randomized, sham-controlled cross-over trial to examine the effect of therapeutic stimulation (verum) vs sham-stimulation (sham) on the pupillary unrest index (PUI). 20 consecutive adults (age 56±9.5 years, 19 men) underwent PST at 9 am (PUI-9) and 1 pm (PUI-13) at least 6 months after implantation regardless of being responder or non-responder to the therapy. For 1 week, the stimulation was at the therapeutic setting (verum) or just above sensation threshold (sham) in randomized order. Stimulation started after patients" sleep onset so that they couldn´t recognize in which group they were currently in. Subjective sleepiness was assessed using the Epworth Sleepiness Scale (ESS). Results:No significant difference in PUI could be detected in comparison of verum to sham stimulation at either time of the measurement (PUI-9 p&lt;0.8; PUI-13 p&lt;0.13). The ESS values did not significantly differ between therapeutic und sham stimulation (p&lt;0.3). The impact of the age of subjects (young&lt;49, old≥50) on the PUI wasn´t significant either. Conclusion:This trial did not detect a significant effect of UAS on the tonic activation, nor the subjective sleepiness. Reasons may be the PST being an inappropriate tool to assess daytime performance in this patient cohort or a lack of significance due to a relevant number of non-responders. Further research is needed.Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.

Impact of respiration synchronized hypoglossal nerve stimulation on pupillographic sleepiness test results

Implantate / Stimulationstherapie

Schlafmedizin

Free lecture

Discussion

Saal Essen

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Joint Meeting with the Spanish-German ENT Society (SDGHNO-SHAORL)

International Session 22

Controversies in Sleep Apnoea Treatment

International Forum

International Session 22
Controversies in Sleep Apnoea Treatment

Termin

Chairs

Thema

Sprache

Programm

International Session 22Controversies in Sleep Apnoea Treatment

Termin

Chairs

Thema

Sprache

Programm

International Session 22
Controversies in Sleep Apnoea Treatment